cutoff - Seek the Significant Cutoff Value
Seek the significant cutoff value for a continuous
variable, which will be transformed into a classification, for
linear regression, logistic regression, logrank analysis and
cox regression. First of all, all combinations will be gotten
by combn() function. Then n.per argument, abbreviated of total
number percentage, will be used to remove the combination of
smaller data group. In logistic, Cox regression and logrank
analysis, we will also use p.per argument, patient percentage,
to filter the lower proportion of patients in each group.
Finally, p value in regression results will be used to get the
significant combinations and output relevant parameters. In
this package, there is no limit to the number of cutoff points,
which can be 1, 2, 3 or more. Missing values will be deleted by
na.omit() function before analysis.